NaturextTM Immune+ AC Essence is made from Antrodia Camphorata Mycelia, a Rare Fungus found naturally only in Taiwan and have been used by the Chinese as a Cancer Preventive Health Supplement for more than 50 years. Antrodia Camphorata is rich in Flavonoids, Terpenoids, Polyphenolics and Polysaccharides. The known main Bioactive Compounds found in AC are: Polysaccharides, Superoxide Dismutase (SOD), and Triterpenes. Triterpenes, the most important Bioactive Ingredient found in AC, is a compound which exhibits Anti-Cancer, Anti-Virus, Anti-Oxidant, Hepatoprotection and Cholesterol Inhibition Properties.

Antrodia Camphorata (AC) is also commonly called the King of Lingzhi. AC is a rare medicinal fungus that grows
naturally inside the Cinnamonum Kanehirae Tree Trunk, a native tree species of Taiwan.

Antrodia Camphorata, is a precious Traditional Chinese Herbal Medicine and shows several Pharmacological Effects
including the inhibition of proliferation and growth in cancer cells, the inhibition of inflammatory response, the
antioxidant and free radical-scavenging activities and the prevention of hepatotoxicity.

New Anti Cancer compound isolated from AC
Recently, scientists isolated an anti cancer compound in AC and patented and named the new bio-active compound
Antroquinonol¹. Various laboratory tests using Antroquinonol^TM show that it was effective against a wide range of
cancerous cells¹. In 2010 March, Antroquinonol^TM was recognized as Breakthrough Drug by the Chinese Ministry of
Science and Technology. Antroquinonol^TM comes with 6 FDA patents and has been approved by the US FDA to enter
into first stage clinical trial.  

References: 1: Planta Med. 2007 Oct;73(13):1412-5. Epub 2007 Oct 11.
"A new cytotoxic agent from solid-state fermented mycelium of Antrodia Camphorata." 

Potentially more potent than Ganoderma Lucidium

Antrodia Camphorata (AC) has been proven to be more potent than Ganoderma Lucidium (Lingzhi) in 
pharmacological activities. Compared to the well known Ganoderma Licudium (Lingzhi) where less than 50 types
of Triterpenes are found, AC contains more than 200 types of Triterpenes. In addition, the concentration of
Triterpenes found in AC is 10-15 times higher than Ganoderma Lucidium.  

Recently, scientists discovered and patented new active anti-cancer compound Antroquinonol. Antroquinonol is a
unique compound found only in AC. Various clinical tests using Antroquinonol proved it effective against
cancerous cells.

Naturext Immune+ AC Essence^TM also uses a patented solid state fermentation process to cultivate Antrodia
Camphorata to ensure highest quality and consistency in its manufacturing process. In vitro experiments have
shown that the cultivated Naturext Immune+ AC Essence^TM with active anti cancer compound Antroquinonol
(0.2% w/w) demonstrated superior anti cancer cell viability performance against wild Antrodia Camphorata.

Isolated from Antrodia Camphorata- High safety, high performance anti cancer compound.

Pharmacological Properties and Modes of Actions:

Antroquinonol^TM could inhibit proferation of liver, lung, breast and prostate cancer cells. Antroquinonol^TM 
induced S phase arrest of HepG2 cells when they are pretreated with synchronization. After synchronization with
Antroquinonol, it decreases all cell cycle regulatory protein and cell growth related protein (including cyclin A,
cyclin D, cyclin E, cdk2, cdk4, Rb, p53, Akt and MAPK). Antroquinonol inhibits protein synthesis through
translation related protein 4E-BP1 and elF4E.

Antroquinonol^TM for the treatment of multiple forms of cancer has been proven in vivo. The compound has
passed in-vivo efficacy, ADME/toxicology for at least three kinds of cancer (NSCLC, liver and breast cancer)
compared with the chemotherapy drugs Mitomycin and Taxol as positive control. No drug resistance was
observed during in-vivo studies. This indicates that the drug can be considered a long-term orally-administered
cancer therapy.